2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

PDF 2.67 MB

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-114969
    Clioxanide
    Clioxanide is a potential anti-liver fluke (Fasciola hepatica) agent. The results showed that Clioxanide showed no efficacy against 4-week-old or 19-week-old flukes at doses of 135 mg/kg or 200 mg/kg. In contrast, hexachloroethane was very effective against older flukes, reaching 100% efficacy at lower doses. The study pointed out that laboratory mice may not be suitable for screening potential compounds against liver fluke infections in ruminants such as cattle and sheep. In addition, no obvious toxic reactions were observed in mice with Clioxanide.
    Clioxanide
  • HY-N18245
    (-)-3-O-Acetylcatechin
    (-)-3-O-Acetylcatechin is a Leishmania amazonensis arginase inhibitor with an IC50 of 3.7 μM. (-)-3-O-Acetylcatechin can be used for the research of leishmaniasis.
    (-)-3-O-Acetylcatechin
  • HY-144297
    HDAC1-IN-3
    HDAC1-IN-3 is a potent Pf HDAC1 inhibitor. HDAC1-IN-3 shows antimalarial activity in wild-type and multidrug-resistant parasite strains. HDAC1-IN-3 shows a significant in vivo killing effect against all life cycles of parasites.
    HDAC1-IN-3
  • HY-101000
    Clazuril
    		Inhibitor
    Clazuril (R62690) has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle.
    Clazuril
  • HY-155549
    Antileishmanial agent-20
    		Inhibitor
    Antileishmanial agent-20 is selective towards Leishmania parasite. Antileishmanial agent-20 has IC50 value of 2.8 μM and 0.2 μM for L. infantum and L. braziliensis, respectively. Antileishmanial agent-20 can be used for parasites research.
    Antileishmanial agent-20
  • HY-121003
    Aspyrone
    Aspyrone is a polyketide fungal metabolite that has been found in Aspergillus and has diverse biological activities. It is active against a panel of 13 fungi when used at a concentration of 20 μg/mL and a panel of 21 bacteria in a disc assay when used at a concentration of 100 μg per disc.1 Aspyrone (10-1,000 mg/L) is nematocidal against P. penetrans.
    Aspyrone
  • HY-184205
    LASSBio-1736
    		Inhibitor
    LASSBio-1736 is a Cysteine protease inhibitor and antimalarial agent. LASSBio-1736 targets the promastigote form of Leishmania major. LASSBio-1736 can be used in the research of leishmaniasis.
    LASSBio-1736
  • HY-141621
    ACT-606559
    		Inhibitor
    ACT-606559, a new chemical entity with antimalarial activity, is a metabolite of ACT451840. ACT-606559 can be used for the research of malarial.
    ACT-606559
  • HY-162833
    Antileishmanial agent-30
    		Inhibitor
    Antileishmanial agent-30 (compound 17k) is a potent inhibitor of leishmania, with the IC50, CC50, and SI of 0.2 μM, >100 μM and >500 for L. donovani.
    Antileishmanial agent-30
  • HY-N11031
    Z-Antiepilepsirine
    		Inhibitor
    Z-Antiepilepsirine is an amide alkaloid that can be found in Piper capense L.f. Z-Antiepilepsirine shows antiplasmodial activity with an IC50 value of 27 µM for W2 strain of Plasmodium falciparum.
    Z-Antiepilepsirine
  • HY-N9475
    Betulonaldehyde
    		Inhibitor
    Betulonaldehyde is a pentacyclic triterpenoid that can be isolated from Diospyros filipendula. Betulonaldehyde has antiplasmodial activity (IC50: 3.36 µg/mL). Betulonaldehyde has cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s: 19.23 and 17.09 µg/mL, respectively). Betulonaldehyde inhibits Phorbol 12-myristate 13-acetate (HY-18739) induced inflammation in mice.
    Betulonaldehyde
  • HY-W739267
    Fenazaquin-d13
    		Inhibitor
    Fenazaquin-d13 (XDE-436-d13) is the deuterium labeled Fenazaquin (HY-117397). Fenazaquin (XDE-436; EL-436) is a quinazoline acaricide.
    Fenazaquin-d<sub>13</sub>
  • HY-12519G
    Oltipraz (GMP)
    		Inhibitor
    Oltipraz (GMP) is Oltipraz (HY-12519) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Oltipraz has an inhibitory effect on HIF-1α activation. Oltipraz is a potent Nrf2 activator.
    Oltipraz (GMP)
  • HY-N0152R
    Myricitrin (Standard)
    		Inhibitor
    Myricitrin (Standard) is the analytical standard of Myricitrin. This product is intended for research and analytical applications. Myricitrin, a naturally occurring flavonoid, is an orally active nitric oxide (NO) and PKC inhibitor. Myricitrin has central nervous system activity, including anxiolytic-like action. Myricitrin possesses antioxidant, anti-inflammatory, antifibrotic and anti-malarial effects.
    Myricitrin (Standard)
  • HY-18746
    KAI-407
    		Inhibitor
    KAI-407 is an orally active inhibitor of Plasmodium PI4K kinase, which can broadly inhibit multiple stages of the parasite lifecycle. KAI-407 exhibits EC50s of for the blood stage of malignant Plasmodium of 81 nM; for the liver schizonts of P. yoelii of 88 nM; and IC50s for the liver schizonts and dormant bodies of P. cynomolgi of 0.64 μM and 0.69 μM respectively. KAI-407 can prevent Plasmodium berghei infection 100%. KAI-407 can be used for the study of vivax malaria.
    KAI-407
  • HY-W740485
    Hexamidine-d12
    		Inhibitor
    Hexamidine-d12 is the deuterium labeled Hexamidine. Hexamidine has amoebicidal effect that can be used for the research of Acanthamoeba keratitis.
    Hexamidine-d<sub>12<sub>
  • HY-W026467
    MMV665916
    		Inhibitor
    MMV665916, a quinazolinedione derivative, is an antimalarial agent. MMV665916 displays antiplasmodial activity against P. falciparum FcB1 strain with EC50 value of 0.4 μM and presents the high selectivity index (SI>250).
    MMV665916
  • HY-B0221A
    Amphotericin B trihydrate
    Amphotericin B trihydrate, a polyene antibiotic, is first isolated from fermenter cultures of Streptomyces nodosus. Amphotericin B trihydrate also possesses antileishmanial activity.
    Amphotericin B trihydrate
  • HY-155103
    Antitrypanosomal agent 15
    		Inhibitor
    Antitrypanosomal agent 15 (compound 26) is an orally active, brain-penetrant, selective inhibitor against Trypanosoma cruzi proteasome, with an pIC50 of 7.4 and <4 for T. cruzi and human proteasome, respectively. Antitrypanosomal agent 15 has favorable ADME properties and can be used for Chagas disease study.
    Antitrypanosomal agent 15
  • HY-W702966
    Ethopabate-d5
    Ethopabate-d5 (Ethyl pabate-d5) is the deuterium labeled Ethopabate (HY-B2138). Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    Ethopabate-d<sub>5</sub>
Parasite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.